This week's newly-posted federal SBIR/STTR topics (June 2026)
A cross-agency snapshot of the SBIR/STTR topics posted within the last ~14 days across DoD, NIH, NSF, DOE, and the rest of the federal R&D apparatus. ITAR/CUI dropped.
Paste a one-paragraph capability statement at /try — TopicScout ranks the open SBIR/STTR topics that actually fit and shows you the rationale per match. No signup, no card.
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Limited Competition: Centers of Biomedical Research Excellence: Expansion/Sustainability Phases (COBRE-E/S) (P30 - Clinical Trial Not Allowed)
National Institutes of Health (HHS-NIH11) · closes 2029-05-25
The Institutional Development Award (IDeA) program supports biomedical research capacity building in states that have historically received low levels of NIH funding. The Centers of Biomedical Research Excellence: Expansion/Sustainability Phases (COBRE-E/S) Notice of Funding Opportunity (NOFO) supports the expansion and sustainability of biomedical…
→ Full topic / applyFiscal Year (FY) 2027 Department of the Navy (DoN) Historically Black Colleges and Universities/Minority Institutions (HBCU/MI) Program
Office of Naval Research (DOD-ONR) · closes 2026-12-11
Key programmatic objectives of the DoN HBCU/MI Program are achieved through the implementation and performance of three program goals:• enhancing the research and educational capabilities of HBCU/MIs in scientific and engineering disciplines critical to the defense mission of the U.S. Navy and U.S. Marine Corps,• encouraging…
→ Full topic / applyDoW Parkinson’s, Investigator-Initiated Research Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-11-06
Summary: The fiscal year 2026 (FY26) Parkinson’s Research Program (PRP) Investigator-Initiated Research Award (IIRA) supports highly rigorous, multidisciplinary, high-impact research projects that have the potential to make an important contribution to Parkinson’s disease research. Research must address at least one of the four FY26 PRP Focus…
→ Full topic / applyDoW Parkinson’s, Early Investigator Research Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-11-06
Summary: The fiscal year 2026 (FY26) Parkinson’s Research Program (PRP) Early Investigator Research Award (EIRA) supports Parkinson’s disease (PD) research for investigators in the early stages of their careers. The FY26 EIRA offers two funding levels, which align to the research career stage of the Principal Investigator (PI). Funding Level…
→ Full topic / applyGREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)
National Institutes of Health (HHS-NIH11) · closes 2026-10-30
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of…
→ Full topic / applyGREGoRi Technology Integration Center (U01, Clinical Trials Optional)
National Institutes of Health (HHS-NIH11) · closes 2026-10-30
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of…
→ Full topic / applyGREGoRi Innovation Projects (U01 Clinical Trial Optional)
National Institutes of Health (HHS-NIH11) · closes 2026-10-30
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding…
→ Full topic / applyDoW Kidney Cancer, Academy of Kidney Cancer Investigators – Early-Career Scholar Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-09-28
Summary: Initially created in fiscal year 2019 (FY19), the Kidney Cancer Research Program (KCRP) Academy of Kidney Cancer Investigators (AKCI) is a unique interactive virtual academy providing intensive mentoring, national networking, collaborations, and a peer group for junior faculty. The Academy pairs Early Career Scholars (ECS) with established…
→ Full topic / applyDoW Kidney Cancer, Idea Development Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-09-28
Summary: The fiscal year 2026 (FY26) Kidney Cancer Research Program (KCRP) Idea Development Award (IDA) supports the development of high-impact ideas that advance the understanding of kidney cancer and ultimately lead to improved patient outcomes. The research project should include a well-formulated, testable hypothesis based on strong scientific…
→ Full topic / applySustaining life-saving HIV services in Ukraine by strengthening resilient health systems under the Ukraine Ministry of Health, Public Health Center
Centers for Disease Control-GHC (HHS-CDC-GHC) · closes 2026-07-20
The Award Ceiling for Year 1 is 0 (none). CDC anticipates an Approximate Total Fiscal Year Funding amount of $10,000,000 for Year 1, subject to the availability of funds.This NOFO aims to help the Public Health Center (PHC) of the Ministry of Health (MOH) enhance life-saving assistance for HIV and associated prevalent health conditions. This should be…
→ Full topic / applyFood Safety Outreach Program-Collaborative Education and Training Projects
National Institute of Food and Agriculture-eRA (USDA-NIFA-ERA) · closes 2026-07-20
In FY 2026, FSOP, under Assistance Listing 10.328, will maintain and continue to expand training, education, outreach, and coordination by soliciting new Collaborative Education and Training Projects.
→ Full topic / applyFood Safety Outreach Program Technical Assistance-Grant Writing Skills Projects
National Institute of Food and Agriculture-eRA (USDA-NIFA-ERA) · closes 2026-07-20
In FY 2026, FSOP, under Assistance Listing 10.328, will maintain and continue to expand training, education, outreach, and coordination by soliciting new Technical Assistance – Grant Writing Skills Projects.
→ Full topic / applyChildren, Youth, and Families at Risk 4-H Military Partnership Professional Development and Technical Assistance
National Institute of Food and Agriculture (USDA-NIFA) · closes 2026-07-20
The purpose of the CMP-PDTA, under assistance listing 10.521, is to support the implementation and capacity of the 4-H Military Partnership and Outreach Support Program. Professional development and technical assistance are provided to the Land-grant Institutions and the CES so that, in collaboration with other organizations, they can develop and deliver…
→ Full topic / applyFood Safety Outreach Program-Community Outreach Projects
National Institute of Food and Agriculture-eRA (USDA-NIFA-ERA) · closes 2026-07-20
In FY 2026, FSOP, under Assistance Listing 10.328, will maintain and continue to expand training, education, outreach, and coordination by soliciting new Community Outreach Projects.
→ Full topic / applyFood and Agriculture Service Learning Program (FASLP)
National Institute of Food and Agriculture-eRA (USDA-NIFA-ERA) · closes 2026-07-20
The purpose of FASLP (Assistance Listing 10.522) is to increase knowledge of agriculture and improve the nutritional health of children.
→ Full topic / applyBiotechnology Risk Assessment Research Grants Program
National Institute of Food and Agriculture (USDA-NIFA) · closes 2026-07-13
The purpose of the BRAG program, Assistance Listing 10.219, is to support the generation of new information that will assist Federal regulatory agencies in making science-based decisions about the ecological effects of introducing genetically engineered (GE) organisms by techniques that use recombinant, synthesized, or amplified nucleic acids to modify…
→ Full topic / applyDoW Orthopaedic, Clinical Research Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-11-18
Summary: The fiscal year 2026 (FY26) Orthopaedic Research Program (ORP) Clinical Research Award (CRA) seeks clinical research that evaluates orthopaedic-specific factors and interventions. The ORP intends for research supported by this mechanism to generate clinically useful evidence with potential to optimize patient outcomes and inform clinical care or…
→ Full topic / applyDoW Orthopaedic, Applied Research Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-11-18
Summary: The Orthopaedic Research Program (ORP) Applied Research Award (ARA) seeks applied research applications focused on advancing optimal treatment and restoration of function for individuals with orthopaedic injuries sustained during combat or service-related activities.Distinctive Features: • Applied research is defined as work that refines…
→ Full topic / applyDoW Rare Cancers Idea Development Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-11-18
Summary: The fiscal year 2026 (FY26) Rare Cancers Research Program (RCRP) Idea Development Award (IDA) promotes ideas that are ready for further development and have the potential to yield high-impact findings and new avenues of investigation.Distinctive Features:The RCRP encourages applicants to include an exploratory aim or sub-aim to support any…
→ Full topic / applyDoW Rare Cancers Resource and Community Development Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-11-18
Summary: The fiscal year 2026 (FY26) Rare Cancers Research Program (RCRP) Resource and Community Development Award (RCDA) supports the development of research resources and clinical or preclinical datasets that will advance the field of rare cancers research and ultimately improve outcomes for individuals with rare cancers. Research supporting this…
→ Full topic / applyDoW Joint Warfighter Medical, Military Medical Research and Development Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-11-16
Summary: The fiscal year 2026 (FY26) Joint Warfighter Medical Research Program (JWMRP) Military Medical Research and Development Award (MMRDA) mechanism is intended to fund the logical continuation of previous Department of War (DOW)-funded research and development efforts relevant to the FY26 JWMRP that augment and accelerate high-priority medical…
→ Full topic / applyDoW Bone Marrow Failure, Investigator-Initiated Research Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-11-04
Summary: Supports studies that further develop mature ideas, expand upon key discoveries, and have the potential to make significant advances in bone marrow (BMF) failure research and/or patient care. Investigator-Initiated Research Award (IIRA) applications may involve translational and clinical research including studies in preclinical models, research…
→ Full topic / applyDoW Bone Marrow Failure, Idea Development Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-11-04
Summary: The BMFRP Idea Development Award (IDA) is intended to support innovative ideas and high-impact approaches based on scientifically sound evidence to move toward the BMFRP’s vision of understanding and curing BMF diseases.Distinctive Features:This funding opportunity is open to Established Investigators (EIs) and Early-Career Investigators…
→ Full topic / applyDoW Bone Marrow Failure, Resource Development Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-11-04
Summary: The fiscal year 2026 (FY26) Bone Marrow Failure Research Program (BMFRP) Resource Development Award (RDA) supports the development of a multiomic atlas generated from well-annotated human bone marrow failure (BMF) samples, with omic data derived from marrow specimens. The resulting dataset should serve as an open-access, durable resource for the…
→ Full topic / applyDoW Rare Cancers Concept Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-09-30
Summary: The fiscal year 2026 (FY26) Rare Cancers Research Program (RCRP) Concept Award (CA) supports highly innovative, untested, potentially groundbreaking novel concepts in rare cancers. Applications must describe how the new idea will be innovative and present as a novel course of investigation in the field of rare cancers.Distinctive…
→ Full topic / applyDoW Duchenne Muscular Dystrophy, Idea Development Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-09-18
Summary: The fiscal year 2026 (FY26) Duchenne Muscular Dystrophy Research Program (DMDRP) Idea Development Award (IDA) promotes new ideas that are still in the early stages of development and have the potential to yield impactful data and new avenues of investigation. This award supports impactful, high-risk/high-reward research that could lead to…
→ Full topic / applyDoW Duchenne Muscular Dystrophy Clinical/Translational Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-09-18
Summary: The fiscal year 2026 (FY26) Duchenne Muscular Dystrophy Research Program (DMDRP) Clinical/Translational Research Award (CTRA) supports advanced translational research to accelerate promising ideas in Duchenne muscular dystrophy (DMD) research toward clinical applications. Research must address at least one of the FY26 CTRA Focus Areas. Research…
→ Full topic / applyTribal Broadband Connectivity Program
DOC NIST ERA (DOC-DOCNISTERA) · closes 2026-09-17
NTIA is soliciting applications for funds remaining under the Tribal Broadband Connectivity Program (TBCP), authorized by the Consolidated Appropriations Act, 2021, Division N, Title IX, Section 905(c), Public Law 116-260, 134 Stat. 1182 (Dec. 27, 2020) (Act), as amended by the Infrastructure Investment and Jobs Act, Division F, Title II, Section 60201,…
→ Full topic / applyNative Entities Grant Program
DOC NIST ERA (DOC-DOCNISTERA) · closes 2026-09-17
NTIA is soliciting applications for the Native Entities Grant Program (“Program”), authorized by the Infrastructure Investment and Jobs Act of 2021, Division F, Title III, Public Law 117-58, 135 Stat. 429, 1209 (November 15, 2021) (codified at 47 U.S.C. §1701, 1721, et seq.) (the “Digital Equity Act of 2021” or…
→ Full topic / applyDoW Reconstructive Transplant, Concept Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-09-16
Summary: The fiscal year 2026 (FY26) Reconstructive Transplant Research Program (RTRP) Concept Award supports the exploration of highly innovative new concepts or untested theories that address an important problem relevant to reconstructive transplantation. The Concept Award does not support clinical trials. Distinctive Features: · Innovation:…
→ Full topic / applyMulti Modal Materials Analysis (MMoMA)
DARPA - Defense Sciences Office (DOD-DARPA-DSO) · closes 2026-08-26
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative solutions in the technical area of materials analysis, including surface and bulk analysis of molecular structure, elemental composition, trace elements and isotope ratios in samples, to be conducted under ambient conditions, without the need for special sample preparation.…
→ Full topic / applyDoW Kidney Cancer, Concept Award
Defense Health Agency Contracting Activity - DHACA (DOD-AMRAA) · closes 2026-07-28
Summary: The fiscal year 2026 (FY26) Kidney Cancer Research Program (KCRP) Concept Award supports highly innovative, untested, potentially groundbreaking concepts, theories, paradigms and/or basic kidney cancer research. This award mechanism supports high-risk studies that have the potential to reveal entirely new avenues for investigation in kidney…
→ Full topic / applyReducing the burden of parasitic infections in the United States through evidence-based prevention and control activities.
Centers for Disease Control - NCEZID (HHS-CDC-NCEZID) · closes 2026-07-17
Reducing the burden of parasitic infections in the United States through evidence-based prevention and control activities.
→ Full topic / applyFY26 Washington Union Station Exterior Lighting Upgrade Project
DOT - Federal Railroad Administration (DOT-FRA) · closes 2026-07-07
The purpose of this award is to fund a Fiscal Year (FY) 2026 Federal-State Partnership for Intercity Passenger Rail – Congressional Directed Spending (CDS) grant for the Washington Union Station Exterior Lighting Upgrade Project (the Project). The Washington Union Station Exterior Lighting Upgrade Project funds Construction and will enhance public…
→ Full topic / applyNIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)
National Institutes of Health (HHS-NIH11) · closes 2029-07-05
This notice of funding opportunity (NOFO) encourages applications for implementation of investigator-initiated, milestone driven clinical trials that need enhanced oversight, and as applicable, include mechanistic studies. Mechanistic work in clinical trials may be of great value because it promotes the understanding of human diseases and the development…
→ Full topic / applyNIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)
National Institutes of Health (HHS-NIH11) · closes 2029-07-05
This Notice of Funding Opportunity (NOFO) will support, through the cooperative agreement mechanism, investigator-initiated observational studies or biomarker validation studies that require prospective collection of data/biospecimens or continued analysis of data/biospecimens.
→ Full topic / applyPredoctoral to Postdoctoral Transition Award (Parent F99/K00 - Clinical Trial Not Allowed)
National Institutes of Health (HHS-NIH11) · closes 2029-04-08
The purpose of this award is to support promising graduate students as they complete their doctoral research training and transition into mentored postdoctoral career development opportunities in research areas relevant to the missions of participating NIH Institutes and Centers.This Notice of Funding Opportunity (NOFO) does not allow candidates to…
→ Full topic / applyHEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
National Institutes of Health (HHS-NIH11) · closes 2029-02-20
The purpose of this Notice of Funding Opportunity (NOFO) is to support the preclinical optimization and development of safe, effective, and non-addictive small molecule and biologic therapeutics for the treatment of pain. The goal of the program is to accelerate the advancement of promising early-stage therapeutic candidates and facilitate their…
→ Full topic / applySilvio O. Conte Digestive Diseases Research Core Centers (P30-Clinical Trial Optional)
National Institutes of Health (HHS-NIH11) · closes 2027-02-10
This Notice of Funding Opportunity (NOFO) invites applications for Silvio O. Conte Digestive Diseases Research Core Centers (DDRCCs). The DDRCCs are part of an integrated program of digestive and liver diseases research support provided by the NIDDK. The purpose of this Centers program is to bring together basic and clinical investigators to enhance…
→ Full topic / applySpecial Program Announcement for Office of Naval Research Research Opportunity: FY27 Communications and Networking Applied Research
Office of Naval Research (DOD-ONR) · closes 2026-11-16
The proposed topic will develop and mature Communications and Networking technologies for Naval operations.Background:A Design for Maritime Superiority (2018) describes an operational architecture for distributed maritime operations (DMO) that "... will provide accurate, timely, and analyzed information to units, warfighting groups, and…
→ Full topic / applyPaste a one-paragraph capability statement at /try — TopicScout ranks the open SBIR/STTR topics that actually fit and shows you the rationale per match. No signup, no card.
Try the live matcher →